| Data | Mandante | Visitante |
Vitória do Mandante |
Empate |
Vitória do Visitante |
|
| 03/05/2022 | Cuiabá | 1x2 | Racing | 26.6 % | 28.3 % | 45.1 % |
| 03/05/2022 | River Plate (Uru) | 1x2 | FBC Melgar | 30.4 % | 29.1 % | 40.6 % |
| 03/05/2022 | Ceará | 3x0 | Deportivo La Guaira | 78.2 % | 17.7 % | 4.1 % |
| 03/05/2022 | General Caballero | 0x4 | Independiente | 5.9 % | 19.4 % | 74.7 % |
| 03/05/2022 | 9 de Octubre | 3x2 | Independiente Medellín | 38.5 % | 22.5 % | 39.0 % |
| 04/05/2022 | Atlético Goianiense | 3x2 | Defensa y Justicia | 58.2 % | 29.9 % | 11.9 % |
| 04/05/2022 | Metropolitanos | 0x1 | Montevidéo Wanderers | 59.7 % | 24.1 % | 16.2 % |
| 04/05/2022 | Antofagasta | 1x2 | LDU Quito | 19.0 % | 16.3 % | 64.7 % |
| 04/05/2022 | Fluminense | 2x1 | Júnior Barranquilla | 39.9 % | 25.2 % | 34.9 % |
| 04/05/2022 | Barcelona (Equ) | 1x1 | Lanús | 47.8 % | 28.4 % | 23.8 % |
| 05/05/2022 | Everton (Chi) | 0x0 | São Paulo | 14.5 % | 23.0 % | 62.5 % |
| 05/05/2022 | Unión Santa Fé | 2x0 | Oriente Petrolero | 88.8 % | 9.2 % | 2.0 % |
| 05/05/2022 | Guaireña | 1x1 | Internacional | 45.8 % | 29.8 % | 24.4 % |
| 05/05/2022 | Universidad Católica (Equ) | 0x1 | Santos | 41.1 % | 24.9 % | 34.0 % |
| 05/05/2022 | Banfield | 0x1 | Unión La Calera | 33.3 % | 44.8 % | 21.8 % |
| 05/05/2022 | Ayacucho | 0x0 | Jorge Wilstermann | 68.4 % | 17.7 % | 13.9 % |
| 17/05/2022 | Banfield | 1x1 | Universidad Católica (Equ) | 25.0 % | 40.8 % | 34.3 % |
| 17/05/2022 | Internacional | 2x0 | Independiente Medellín | 54.2 % | 22.0 % | 23.8 % |
| 17/05/2022 | Ceará | 6x0 | General Caballero | 88.5 % | 9.5 % | 2.0 % |
| 17/05/2022 | Júnior Barranquilla | 2x0 | Oriente Petrolero | 88.7 % | 7.7 % | 3.7 % |
| 17/05/2022 | 9 de Octubre | 2x3 | Guaireña | 40.5 % | 24.9 % | 34.6 % |
| 17/05/2022 | Atlético Goianiense | 1x0 | Antofagasta | 88.6 % | 9.8 % | 1.6 % |
| 18/05/2022 | River Plate (Uru) | 1x2 | Cuiabá | 47.0 % | 26.8 % | 26.2 % |
| 18/05/2022 | Racing | 1x0 | FBC Melgar | 52.7 % | 26.1 % | 21.2 % |
| 18/05/2022 | Santos | 1x0 | Unión La Calera | 60.7 % | 25.0 % | 14.3 % |
| 18/05/2022 | LDU Quito | 2x2 | Defensa y Justicia | 52.2 % | 20.3 % | 27.5 % |
| 18/05/2022 | Ayacucho | 0x2 | Everton (Chi) | 44.9 % | 32.9 % | 22.2 % |
| 19/05/2022 | Unión Santa Fé | 0x0 | Fluminense | 37.6 % | 37.7 % | 24.7 % |
| 19/05/2022 | Independiente | 4x0 | Deportivo La Guaira | 81.2 % | 15.3 % | 3.5 % |
| 19/05/2022 | Metropolitanos | 2x2 | Barcelona (Equ) | 12.7 % | 32.9 % | 54.4 % |
| 19/05/2022 | Lanús | 1x2 | Montevidéo Wanderers | 72.5 % | 18.4 % | 9.1 % |
| 19/05/2022 | São Paulo | 3x0 | Jorge Wilstermann | 86.2 % | 11.3 % | 2.6 % |
| 24/05/2022 | Santos | 1x1 | Banfield | 69.6 % | 24.6 % | 5.9 % |
| 24/05/2022 | Unión La Calera | 3x2 | Universidad Católica (Equ) | 49.6 % | 28.3 % | 22.1 % |
| 24/05/2022 | Defensa y Justicia | 0x2 | Antofagasta | 74.5 % | 15.8 % | 9.8 % |
| 24/05/2022 | LDU Quito | 1x1 | Atlético Goianiense | 44.1 % | 25.0 % | 30.8 % |
| 24/05/2022 | Internacional | 5x1 | 9 de Octubre | 67.5 % | 22.0 % | 10.5 % |
| 24/05/2022 | Independiente Medellín | 1x1 | Guaireña | 37.2 % | 20.4 % | 42.3 % |
| 25/05/2022 | São Paulo | 1x0 | Ayacucho | 81.7 % | 12.5 % | 5.8 % |
| 25/05/2022 | Lanús | 1x0 | Metropolitanos | 61.4 % | 31.0 % | 7.6 % |
| 25/05/2022 | Jorge Wilstermann | 0x2 | Everton (Chi) | 11.1 % | 37.0 % | 52.0 % |
| 25/05/2022 | Montevidéo Wanderers | 0x0 | Barcelona (Equ) | 37.5 % | 22.7 % | 39.7 % |
| 25/05/2022 | Deportivo La Guaira | 0x1 | General Caballero | 69.3 % | 17.7 % | 13.1 % |
| 25/05/2022 | Independiente | 0x2 | Ceará | 40.9 % | 28.3 % | 30.8 % |
| 26/05/2022 | Racing | 0x1 | River Plate (Uru) | 79.7 % | 17.7 % | 2.6 % |
| 26/05/2022 | FBC Melgar | 3x1 | Cuiabá | 60.4 % | 22.4 % | 17.3 % |
| 26/05/2022 | Oriente Petrolero | 1x10 | Fluminense | 9.4 % | 15.2 % | 75.4 % |
| 26/05/2022 | Júnior Barranquilla | 0x4 | Unión Santa Fé | 54.3 % | 34.8 % | 11.0 % |
| 28/06/2022 | Nacional (Uru) | 2x0 | Unión Santa Fé | 24.7 % | 47.2 % | 28.1 % |
| 28/06/2022 | Colo Colo | 2x0 | Internacional | 14.6 % | 20.7 % | 64.7 % |
| 29/06/2022 | Táchira | 1x1 | Santos | 7.7 % | 16.4 % | 75.9 % |
| 29/06/2022 | Deportivo Cali | 0x0 | FBC Melgar | 29.4 % | 27.9 % | 42.7 % |
| 29/06/2022 | The Strongest | 1x2 | Ceará | 23.8 % | 24.0 % | 52.2 % |
| 30/06/2022 | Universidad Católica | 2x4 | São Paulo | 24.3 % | 25.3 % | 50.4 % |
| 30/06/2022 | Olímpia | 2x0 | Atlético Goianiense | 9.9 % | 26.3 % | 63.8 % |
| 30/06/2022 | Independiente del Valle | 2x1 | Lanús | 42.4 % | 30.4 % | 27.2 % |
| 05/07/2022 | Unión Santa Fé | 1x2 | Nacional (Uru) | 35.2 % | 40.8 % | 24.0 % |
| 05/07/2022 | Internacional | 4x1 | Colo Colo | 59.7 % | 22.9 % | 17.4 % |
| 06/07/2022 | Santos | 1x1 | Táchira | 67.4 % | 21.2 % | 11.4 % |
| 06/07/2022 | FBC Melgar | 2x1 | Deportivo Cali | 59.4 % | 28.7 % | 11.9 % |
| 06/07/2022 | Ceará | 3x0 | The Strongest | 74.1 % | 17.0 % | 8.8 % |
| 07/07/2022 | São Paulo | 4x1 | Universidad Católica | 73.9 % | 16.1 % | 9.9 % |
| 07/07/2022 | Atlético Goianiense | 2x0 | Olímpia | 64.5 % | 26.1 % | 9.4 % |
| 07/07/2022 | Lanús | 0x0 | Independiente del Valle | 47.1 % | 28.5 % | 24.4 % |
| 02/08/2022 | Táchira | 0x1 | Independiente del Valle | 23.2 % | 23.2 % | 53.6 % |
| 02/08/2022 | Nacional (Uru) | 0x1 | Atlético Goianiense | 49.6 % | 27.7 % | 22.7 % |
| 03/08/2022 | São Paulo | 1x0 | Ceará | 58.8 % | 20.7 % | 20.5 % |
| 09/08/2022 | Independiente del Valle | 4x1 | Táchira | 75.3 % | 17.6 % | 7.1 % |
| 09/08/2022 | Atlético Goianiense | 3x0 | Nacional (Uru) | 52.9 % | 28.8 % | 18.3 % |
| 10/08/2022 | Ceará | 2x1 | São Paulo | 36.0 % | 25.2 % | 38.8 % |
| 11/08/2022 | Internacional | 0x0 | FBC Melgar | 35.3 % | 34.9 % | 29.8 % |
| 31/08/2022 | Independiente del Valle | 3x0 | FBC Melgar | 42.7 % | 33.0 % | 24.3 % |
| 01/09/2022 | Atlético Goianiense | 3x1 | São Paulo | 37.8 % | 26.7 % | 35.4 % |
| 07/09/2022 | FBC Melgar | 0x3 | Independiente del Valle | 32.0 % | 31.1 % | 36.9 % |
| 08/09/2022 | São Paulo | 2x0 | Atlético Goianiense | 43.7 % | 25.0 % | 35.3 % |
| 01/10/2022 | São Paulo | 0x2 | Independiente del Valle | 45.7 % | 26.1 % | 28.3 % |